Drug Targeting Consider a Lead for Drug Discovery for Example Drug Antagonists

Authors

  • Rezk R. Ayyad Pharmaceutical Medicinal Chemistry Department, Faculty of Pharmacy, ALAZHAR University, Cairo, Egypt
  • Ahmed M. Mansour Pharmacology and Toxicology Department, Faculty of Pharmacy, ALAZHAR University, Cairo, Egypt
  • Ahmed M. Nejm Pharmaceutical Medicinal Chemistry Department, Faculty of Pharmacy, ALAZHAR University, Cairo, Egypt
  • Yasser Abdel Allem Hassan Pharmaceutics and Pharmaceutical Technology Department, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, Addaqahlya, Egypt
  • Ahmed R. Ayyad Faculty of Medicine, Asfendiyarov Kazakh National Medical University (KazNMU), Almaty, Kazakhstan

Keywords:

adrenergic, adrenergic blockers, alpha blockers, beta blockers, cholinergics, anti-cholinergic, drug targeting, drug discovery

Abstract

The adrenergic compounds are chemical structures related to Adrenaline and Noradrenaline e.g., isoprenaline and terbutaline, when want to change in the chemical structure of adrenergic will lead us to an adrenergic blocking agents e.g., Alpha blockers and Beta blockers (prazosin, terazosin, propranolol and atenolol). Also, cholinergic agents especially direct cholinergics are chemical structures related to Acetylcholine which when manipulate of the Ach. We obtain anti-cholinergic agents like neostigmine, physostigmine, pilocarpine… etc. All the blockers are examples of drug discovery depends on Drug targeting (Alpha receptor, Beta receptor, Muscarinic receptor, Nicotinic receptor).

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Published

2024-12-30

How to Cite

Rezk R. Ayyad, Ahmed M. Mansour, Ahmed M. Nejm, Yasser Abdel Allem Hassan, & Ahmed R. Ayyad. (2024). Drug Targeting Consider a Lead for Drug Discovery for Example Drug Antagonists. ournal of rogress in ngineering and hysical cience, 3(4), 1–8. etrieved from https://www.pioneerpublisher.com/jpeps/article/view/1118

Issue

Vol. 3 No. 4 (2024): December

Section

Articles