The Isomers of Some Drugs One Effective and the Other Is Toxic or Ineffective

Authors

  • Rezk R. Ayyad Faculty of Pharmacy, AL- Azhar University, Cairo, Egypt
  • Ahmed M. Nejm Faculty of Pharmacy, AL- Azhar University, Cairo, Egypt
  • Ahmed R. Ayyad Asfendiarof Medical University, Almaty, Kasakhstan

Keywords:

Levo, Dextro, R, S, Cis, Trans, Stereo, effective, pharmacological active, toxicity, racemic mixture

Abstract

The human body has the heart, which is Levo, and the gastrointestinal tract, with the liver in the Dextro position. The carbohydrates in our food are Dextro, and the amino acids in our food are Levo; hence, the isomers of compounds taken by humans may be harmful or ineffective. As a result, we will investigate some drugs in which one of its isomers is effective while the other is ineffective, such as Levo and Dextro-Ethambutol, Levo and Dextro-Dopa, Levo and Dextro-Amphetamine, Dextro and Levo-Rabeprazole, Cis and Trans-Platin, R and S-Hexobarbital, R and S-Fluoxetine.

It may be that each isomer has one pharmacological difference from the other isomer, e.g., quinine and quinidine, and R and S-propafenone.

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Published

2023-05-26

Issue

Vol. 2 No. 2 (2023): June

Section

Articles