The Progress of Common Treatments and Research for Androgenetic Alopecia

Authors

  • Shanshan Chen China Pharmaceutical University, Nanjing, Jiangsu, China
  • Yingjie Sun China Pharmaceutical University, Nanjing, Jiangsu, China
  • Jianxing Liu China Pharmaceutical University, Nanjing, Jiangsu, China
  • Wenjing Yan China Pharmaceutical University, Nanjing, Jiangsu, China
  • Jiakun Liu China Pharmaceutical University, Nanjing, Jiangsu, China
  • Wenjun Hu China Pharmaceutical University, Nanjing, Jiangsu, China

Keywords:

androgenetic alopecia, finasteride, androgen receptor degrader drugs, research advances

Abstract

Androgenetic alopecia (AGA) is the most common type of hair loss, in which patients mostly present with a state of a receding hairline on the forehead. It brings a great mental burden to the patient. Androgenetic alopecia is caused by the combination of dihydrotestosterone (DHT) and androgen receptors (AR), disrupting the hair follicle cycle and minimizing hair follicles. The major treatments currently available include finasteride, minoxidil, hair transplantation, Platelet-rich plasma (PRP), stem cell therapy, etc. This article reviews the mechanism of AGA and the existing major treatments. The author suggested that androgen receptor degrader drugs have good prospects for application among those of various therapeutic options.

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Published

2023-05-12

Issue

Vol. 2 No. 2 (2023): June

Section

Articles