The Application of IgG-Based Elimination Diets in the Intervention of Children with ADHD

Abstract

ADHD is a prevalent neurodevelopmental disorder characterized by inattention, hyperactivity, and impulsivity, significantly affecting children’s academic, social, and emotional well-being. While pharmacological and behavioral interventions are common, they often come with limitations, prompting interest in alternative approaches. IgG-based elimination diets have emerged as a promising strategy, targeting food sensitivities linked to elevated IgG antibodies. These diets aim to reduce systemic inflammation, improve gut health, and alleviate ADHD symptoms by identifying and eliminating IgG-reactive foods. Preliminary evidence suggests potential benefits, including reduced symptom severity and enhanced behavioral and cognitive outcomes, mediated by mechanisms related to the gut-brain axis. However, the approach is controversial due to the lack of standardized IgG testing protocols, questions about the clinical relevance of IgG antibodies, and risks of nutritional deficiencies and social implications associated with restrictive diets. This paper critically evaluates the scientific rationale, efficacy, challenges, and practical applications of IgG-based elimination diets in ADHD management. It emphasizes the need for further rigorous, large-scale studies to validate this intervention and provides guidance on integrating it within a comprehensive ADHD management framework. The findings offer insights into the potential of dietary modifications as a personalized and integrative approach to ADHD care.