Effectiveness of Antiretroviral Therapy in Adolescents with HIV in South Africa

Abstract

Adolescents living with HIV in South Africa face significant challenges in accessing and adhering to antiretroviral therapy (ART), despite its proven effectiveness in improving clinical outcomes. This study explores the prevalence of HIV among adolescents, current ART strategies, clinical effectiveness, barriers to accessibility and adherence, and innovative solutions to enhance outcomes. Key findings highlight the need for targeted interventions to address systemic and psychosocial challenges, including stigma, mental health issues, and disparities in healthcare access. Innovative approaches, such as digital tools, integrated mental health services, and strengthened partnerships between governments, NGOs, and communities, are essential for ensuring sustainable and equitable ART delivery. These strategies offer a pathway to improving health outcomes and quality of life for adolescents living with HIV in South Africa.