Neurobiological and Functional Outcomes of the Interpersonal Whole-Brain Model of Care in Autism Spectrum Disorder: A Mixed-Methods Study

Authors

  • Amy O’ Dell The Jacob’s Ladder Group, US
  • Allegra Saunders The Jacob’s Ladder Group, US
  • Julian Gonzalez The Jacob’s Ladder Group, US
  • Holly A. Haynes The Jacob’s Ladder Group, US; Fresno Pacific University, US

Keywords:

autism spectrum disorder, neurodevelopment, QEEG, brain connectivity, behavioral outcomes, emotional recognition, primitive reflexes, interhemispheric communication

Abstract

The Interpersonal Whole-Brain Model of Care (IWBMC™) presents a comprehensive intervention for autism spectrum disorder (ASD) targeting neurobiological frameworks. This mixed-methods study evaluated its efficacy through QEEG connectivity analysis of a longitudinal case study and pre-post outcomes from 61 ASD clients. Results demonstrated normalization of brain connectivity patterns alongside statistically significant improvements with large effect sizes across behavioral regulation (d=1.26), emotional recognition (d=0.98), cognitive functioning (d=0.84), and neurophysiological integration (d=1.52). The concurrent improvement in brain connectivity and functional outcomes suggests that the IWBMC™’s integrated approach effectively addresses both neurological underpinnings and behavioral manifestations of ASD, offering promising pathways for intervention.

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Published

2025-04-07

Issue

Vol. 3 No. 1 (2025): June

Section

Articles